Sorry, you need to enable JavaScript to visit this website.
تجاوز إلى المحتوى الرئيسي

Claudiu Supuran

Name

Claudiu Supuran

Email

supuran@ksu.edu.sa

Address

Department of Chemistry, College of Science, Building (5)

Office: 2A146

Telephone: 4675992

Project Title

Dendrimers conjugated with carbonic anhydrase inhibitors and activators functionalities

Project Summary

Various dendrimers (low and high molecular weight) will be derivatized with carbonic anhydrase (CA, EC 4.2.1.1) inhibitors and activators functionalities. The CA inhibitors will include sulfonamides, sulfamates, sulfamides, coumarins and dithiocarbamates/xanthates. The CA activators will include amines, amino acids and oligopeptides. These dendrimers will be tested for their activity on a large number of mammalian (human), bacterial, fungal and archaeal CAs, and the active ones may be tsted for in vivo action as antiglaucoma and antitumor agents/diagnostic tools.

تاريخ آخر تحديث : يناير 12, 2023 2:29ص